中文摘要：

目的观察伴有慢性淋巴细胞性甲状腺炎（CLT）的甲状腺微小乳头状癌（PTMC）的临床病理特征及其淋巴结转移情况。方法收集山东大学附属省立医院甲状腺外科2008年1月至2012年1月行手术切除的571例PTMC的临床病理资料,根据是否伴有CLT将其分为PTMC组（435例）和PTMC＋CLT组（136例）两组,比较两组间淋巴结转移率的差异。结果两组颈部淋巴结转移率差异无统计学意义,但PTMC＋CLT组患者的多灶性发生率高于PTMC组（40.4%比21.2%,P〈0.05）,淋巴结转移率低于PTMC组（30.9%比52.2%,P〈0.05）。结论 PTMC的发生可能与其伴发的CLT有关,尽管病灶常为多灶性发生,但其预后较好,可能与其较低的淋巴结转移率相关。

英文摘要：

Objective To investigate the clinicopathological characteristics of papillary thyroid micro-carcinoma（PTMC） associated with chronic lymphocytic thyroiditis（CLT）and the status of lymph node metas-tasis（ LNM） .Methods Clinical data of 571 patients with PTMC underwent surgery in Department of Thy-roid Surgery,Shandong Provincial Hospital Affiliated to Shandong University from Jan.2008 to Jan.2012 with PTMC were retrospectively analyzed,all the cases were divided into PTMC group（435 cases） and PTMC＋CLT group（136 cases） according to whether PTMC was associated with CLT.The difference of LNM rate was observed between the two groups.Results There was no statistically significant difference of neck LNM rate between the two groups（P〉0.05）.However,the multifocal incidence of PTMC＋CLT group was higher than PTMC group（40.4% vs 21.2%, P〈0.05）,while the LNM rate was lower than PTMC group（30.9%vs 52.2%,P 〈0.05）.Conclusion CLT is closely related to the carcinogenesis of PTMC.Although the lesions associated with CLT are often multifocal, the prognosis of PTMC associated with CLT is better than simple PTMC,indicating low rate of LNM may play an important role in improving the outcome of PTMC.