中文摘要：

表观遗传学是研究没有DNA序列变化的、可遗传的基因表达改变。表观遗传修饰可以参与多种生命过程，其在糖脂代谢中也发挥了重要的作用。生物体内的糖脂代谢关系密切，糖脂代谢紊乱会导致多种代谢性疾病的发生。文章主要从DNA甲基化、组蛋白修饰、非编码RNA调控等方面综述了表观遗传修饰在糖脂代谢中的研究进展。

英文摘要：

Epigenetics refers to heritable changes in gene expression without alteration of the DNA sequence. Epigenetic changes play an important role in a variety of biological processes including glucose and lipid metabolism. Glucose and lipid metabolism is closely related each other in vivo and abnormal lipid and glucose metabolism is able to cause multiple metabolic related diseases. This review focuses on recent advances of DNA methylation, histone modification, and non-coding RNA on regulating glucose and lipid metabolism.