中文摘要：

使用迈克尔逊干涉仪,针对光学相干层析成像（OCT,optical coherence tomography）非侵入性成像的特点,设计并建立了一种OCT系统。使用建立的OCT系统测量生理水平上葡萄糖溶液的浓度,研究干涉图像波面的最高点与最低点之间的距离和样品浓度的相关情况。在实验室条件下,使用5%葡萄糖溶液和生理盐水得到生理水平的测量样品,测量结果的线性系数达到0.999 8,方差为0.003 9。实验结果表明,使用OCT系统,利用干涉图像波面的最高点与最低点之间的距离和样品浓度的相关性能精确快速测出葡萄糖溶液的浓度,为糖尿病患者的血糖无损监测提供了一种新思路。

英文摘要：

Optical coherence tomography （OCT） is one of the rapidly developed techniques for bio-tomo- graphy in the last few decades. It can acquire the high resolution cross-section image of micro mechanism in the interior organism tissue. Due to its advantages,including rapid imaging, non-invasive detecting and high resolution,it has been widely applied in biomedical fields, especially in early diagnosis and dynamic monitoring for the systems of eyes, skin, oral cavity and cardiovascular. The Michelson interferometer for optical coherence tomography technology is uesed, an OCT system is designed and combined. The physi- cal level concentrations of glucose solutions are measured. The relationship between the distance of the interference wave images on the highest and the lowest and the sample concentration is explored. In the laboratory, the samples on physiological level are obtained from the compound 5 % glucose solution. The results show that the linear coefficient is 0. 999 8, and the standard deviation is 0. 003 9. Using OCT sys- tem by the related features between sample concentration and the distance of interference image wave from the highest to the lowest can measure the concentration of glucose solution accurately and rapidly. This new method can be used for the study of non-invasive blood glucose measurement instrument.