Passerini反应是一类重要的多组分反应,通过该反应可以合成许多重要的天然产物、复杂分子及药物分子,具有很好的使用价值和应用前景。本文从非对映选择性、立体选择性及应用等方面综述了Passerini反应近年来的研究进展。
Passerini reaction is an important multicomponent reaction,and there are good applied values and wide foregrounds for the reaction. Many important natural products,complicated molecules and drug molecules can be synthesized by using this reaction. The review summarizes the progress in the research of Passerini reaction from diastereoselective,enantioselective approach and its application.