Synthesis of Novel gem-Difluoromethylene-containing 1,2,3-Triazoles via Click Reaction
- ISSN号:1001-604X
- 期刊名称:《中国化学:英文版》
- 分类:O626.26[理学—有机化学;理学—化学] TB333[一般工业技术—材料科学与工程]
- 作者机构:[1]Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
- 相关基金:Project supported by the National Natural Science Foundation of China (No. 21072057), the Key Project in the National Science & Technology Pillar Program of China in the Twelfth Five-year Plan Period (No. 2011BAE06B05), and the Shanghai Leading Academic Discipline Project (No. B507).
关键词:
反应合成, 创业板, 三唑, 末端炔烃, MOL, gem-difluoromethylene-containing 1,2,3-triazoles, click reaction, ethyl 2-azido-2,2-difluoroacetate CuI
中文摘要:
十七新奇 gem-difluoromethylene-containing 1,2,3-triazoles 被乙醇 2-azido-2,2-difluoroacetate 和终端炔属羟的按反应面对 10 mol% CuI 综合。
英文摘要:
Seventeen novel gem-difluoromethylene-containing 1,2,3-triazoles were synthesized by the click reaction of ethyl 2-azido-2,2-difluoroacetate and terminal alkynes in the presence of 10 mol% CuI.