与 nanosciences 和纳米技术的快速的发展,许多生产 nanomaterials 现在在商品,制药学,化妆品,生物医学的产品,和工业被使用。当时 nanomaterials 比疏松物质拥有更多的新奇、唯一的物理化学的性质,他们也在人的健康上有无法预言的影响。在药理学和 nanomaterials 的毒物学研究,在 vivo 知道基本行为是必要的,即这些的吸收,分发,新陈代谢,和排泄(ADME ) 最新设计了材料。Radiotracer 技术很好特别被适合到如此的研究并且得到了机会表明他们的陶醉。在这篇论文,为碳 nanomaterials 的无线电标记方法,金属性并且金属氧化物 nanoparticles,等等被总结,收音机的应用在药理学把 nanomaterials 标记,毒物学研究被构画出。
With the rapid development of nanosciences and nanotechnology, a wide variety of manufactured nanomaterials are now used in commodities, pharmaceutics, cosmetics, biomedical products, and industries. While nanomaterials possess more novel and unique physicochemical properties than bulk materials, they also have an unpredictable impact on human health. In the pharmacology and toxicology studies of nanomaterials, it is essential to know the basic behavior in vivo, i.e. absorption, distribution, metabolism, and excretion (ADME) of these newly designed materials. Radiotracer techniques are especially well suited to such studies and have got the chance to demonstrate their enchantment. In this paper, radiolabeling methods for carbon nanomaterials, metallic and metal oxide nanoparticles, etc. are summarized and the applications of the radiolabeled nanomaterials in pharmacology and toxicology studies are outlined.