位置：成果数据库 > 期刊 > 期刊详情页
Discovery of highly potent novel antifungal azoles by structure-based rational design
  • 期刊名称：Bioorg Med Chem Letter
  • 时间：2009
  • 页码：5965-5969
  • 相关项目：抗真菌药物类药性优化设计平台的创建及先导化合物的优化设计研究
作者： 张万年|Wang W|Sheng C|Che X|Ji H|Cao Y|Miao Z|Yao J|Zhang W|
同期刊论文项目
抗真菌药物类药性优化设计平台的创建及先导化合物的优化设计研究
期刊论文 21
同项目期刊论文
New Lead Structures in Antifungal Drug Discovery
Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping
New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel An
Structure-based design,synthesis,and antifungal activity of new triazole derivatives
Asymmetric Synthesis,Antifungal Activity and Molecular Modeling of Iodiconazole Isomers
Improve Model of Lanosterol 14alpha-Demethylase by Ligand-Supported Homology Modeling:Validation by
Total synthesis and structure-activity relationships of new echinocandin-like antifungal cyclolipohe
Design, Synthesis and Structure-Activity Relationships of New Triazole Derivatives Containing N-Subs
Fragment Informatics and Computational Fragment-based Drug Design: An Overview and Update.
Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel In
Total synthesis and structure-activity relationships of caspofungin-like macrocyclic antifungal lipo
Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-based Virtual Screening an
A New Strategy To Improve the Metabolic Stability of Lactone:Discovery of (20S,21S)-21-Fluoraocampto
New Stuategies in the Discovery of Novel Non-Camptothecin Topoisomerase I Inhibitors
Novel Conformationally Restricted Triazole Derivatives with Potent Antifungal Activity
Structure-based rational design,synthesis and antifungal activity of oxime-containing azole derivati
Design and Synthesis of Novel Triazole Antifungal Derivatives by Structure-based Bioisosterism
Evolutionary trace analysis of CYP51 family: implication for site-directed mutagenesis and novel ant
Discovery of highly potent triazole antifungal derivatives by heterocycle-benzene bioisosteric repla
基于片段的药物设计方法研究进展