欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
目的 探讨多发性骨髓瘤患者血清血小板生成素（TPO）水平与血小板数的关系及其意义。方法 采用夹心酶联免疫法测定14例健康人、10例多发性骨髓瘤患者化疗前、化疗后血清TPO，同时检测血小板数。结果 多发性骨髓瘤化疗前组、化疗后组TPO、PLT值均低于对照组，TPO水平化疗后组高于化疗前组，TPO水平与PLT数均呈不相关。结论 多发性骨髓瘤并血小板减少患者，使用rhTPO治疗血小板减少可能有效，化疗前开始rhTPO使用可能提升血小板数量更明显。
英文摘要：
Objective To study the relationship between the levels of serum TPO and the number of peripheral blood platelet （PLT） in patients of multiple myeloma （MM） and their clinical implication. Methods The levels of TPO and blood platelet were detected in 10 patients and 14 healthy persons by using sandwich ELISA and automatic hemocytoanalyser. Result The serum TPO levels and blood platelet are markedly lower in multiple myeloma patients than that in control. The leveIs of TPO in multiple myeloma patients after chemotherapy is higher than that before chemotherapy. The levels of TPO and the numbe of blood platelet are not correlated in patients with multiple myeloma. Conclusions The multiple myeloma patients with thrombecytopenia treat with rhTPO may be useful. Beginning to.use rhTPO before chemotherapy may increase number of PLT much more efficiently.
同期刊论文项目
同项目期刊论文
期刊信息
位置：