位置：成果数据库 > 期刊 > 期刊详情页
L-Prolinamide Catalyzed Aqueous Direct Aldol Reaction： an Environment-friendly Method for the Synthesis of β- Hydroxyl keto nes
  • ISSN号：1001-604X
  • 期刊名称：《中国化学：英文版》
  • 时间：0
  • 分类：O623.511[理学—有机化学;理学—化学]
  • 作者机构：[1]Key Laboratory of Green Chemistry, Jiangxi Province and Department of Chemistry, Jiangxi Normal University, Nanchang, Jiangxi 330027, China, [2]Department of Chemistry and State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China, [3]Key Laboratory of Poyang Lake Ecological Environment and Resource Development, Jiangxi Normal University, Nanchang, Jiangxi 330027, China
  • 相关基金：Project supported by the National Natural Science Foundation of China （Nos. 20342007, 20462003, 20452001 and 20421202）.
作者： 彭以元[1,3], 刘汉[1], 崔明[1], 程津培[2]
关键词： 丁间醇醛反应, 绿化学, 脯氨酰胺, 环境方法, aldol reaction, L-prolinamide, β-hydroxylketone, green chemistry
中文摘要：

环境友好的 L-prolinamide 催化丁间醇醛反应被开发了。反应展出了宽广底层概论，并且有好 diastereoselectivity 的高收益为周期的酉同类被获得。产品隔离的简洁，是的水的用法环境地良性的反应媒介，和用法便宜，容易地可得到并且 recyclable 催化剂使这个过程有希望为氢氧根酉同类的大规模准备被发展。

英文摘要：

An environment-friendly L-prolinamide catalyzed aldol reaction has been developed. The reaction exhibited broad substrate generality, and high yields with good diastereoselectivity were obtained for cyclic ketones.The simplicity of product isolation, usage of water as environmentally benign reaction medium, and the usage of cheap, readily available and recyclable catalyst make this process promising to be developed for large-scale preparation of β-hydroxyl ketones.

同期刊论文项目
绿色溶剂中氨基酸及多肽催化不对称直接aldol类反应研究
期刊论文 11
水相及胶束中氨基酸及多肽直接催化aldol类型反应
期刊论文 3
环境友好介质中有机小分子催化反应研究
期刊论文 14
功能有机分子的构筑和构效关系研究
期刊论文 186
同项目期刊论文
丁酮与硝基苯甲醛反应生成的aldol产物的NMR表征方法及其应用
An Environmentally Benign System for Synthesis of β-Hydroxylketones： L-Histidine Asymmetrically Catalyzed Direct Aldol Reactions in Aqueous Micelle and Water-like Media
Remarkable Rate Acceleration o
Functionalised Chiral Ionic Li
The azoles: effective catalyst
水溶液中铵离子pK_a值的理论计算
An Environmentally Benign System for Synthesis of β-Hydroxylketones： L-Histidine Asymmetrically Catalyzed Direct Aldol Reactions in Aqueous Micelle and Water-like Media
Chiral Br?nsted acid catalyzed
Metal-catalyzed copolymerizati
The interaction between tyloph
Formation of aluminacyclobuten
Development of a general quant
Triaryl phosphine-functionaliz
A structurally simple L-prolin
Insecticidal benzoylphenylurea
Fluorescence Quenching Study of Zinc Bisporphyrins by Fulleropyrrolidines and Their N-Oxides
Synthesis of ferrocenoylphenyl
Synthesis and bioassay evaluat
Highly efficient Rh(I)-catalyz
Isolation of a 1, 2- dialumina
The modification of bis(pyrazo
Study on structure-activity re
手性螺环单磷配体在不对称氢甲酰
四氯化锡诱导的Prins环化法高选
全甲基及其多胺修饰环糊精与牛血
三嗪基苯胺桥联双环糊精的合成及
A poly(ethylene glycol)-suppor
Cong-wei Niu, Yan-zhen He, Gua
Surfactant-type asymmetric org
Hongtao Mu, Stimulation activi
Interaction of bulged DNA with
The structures and thermodynam
A water-soluble (-cyclodextrin
Synthesis of cyclic carbonates
Organic solvent-free process f
Asymmetric Friedel–Crafts add
New chiral phosphorus ligands
Negative kinetic temperature e
SnCl2-mediated carbonyl allyla
Intermolecular complexation th
Water-filled channels construc
Synthesis of some selenacrown
Herbert W. Roesky, C-H Activat
Secondary assembly of bile sal
Thio[2-(benzoylamino)ethylamin
Highly enantioselective hydrov
New multidentate heteroscorpio
The structure and thermodynami
The first air-stable and effic
Unique conformation and packin
Enantioselective rhodium-catal
Quaternary ammonium salt-funct
Supercritical carbon dioxide a
Nanoarchitectures constructed
Synthesis and insecticidal eva
Synthesis and structures of di
Synthesis and structures of ar
Sn-catalyzed synthesis of prop
Group 6 metal carbonyl complex
Asymmetric reductive coupling
Thermodynamics of interactions
Selective binding thermodynami
A unique tetramer of 4:5 (-cyc
Cooperative binding and multip
1,3-Dichlorotetra-n- butyldist
Interaction and CoMFA studies
A simple primary-tertiary diam
Well-defined chiral spiro Ir/p
Functionalized chiral ionic li
Bundle-shaped cyclodextrin-Tb
A simple method for epoxidatio
Cyclodextrins as carriers for
Crystal structures of two cali
A general synthetic route to 6
Asymmetric Friedel–Crafts alk
侧链含有Mn-Re双核过渡金属基团
Supramolecular assemblies of s
Controllable DNA condensation
Highly enantioselective insert
Highly enantioselective silylc
Cyclodextrin-driven movement o
Ionic liquid-immobilized quinu
Copper-catalyzed asymmetric ri
Fluorescence sensing and bindi
A general synthetic route to c
Asymmetric aldol reactions cat
Preparation and application of
Hydroxyl ionic liquid (HIL)-im
Highly efficient triaryl phosp
A novel supramolecular assembl
Palladium-catalyzed asymmetric
Indium triflate catalyzed ally
One-pot tandem Barbier-Prins s
Facile generation of aluminum
Reactions of pyridyl side-chai
Functionalized ionic liquids c
1,1,1,3,3,3-Hexamethyltrisilan
双臂式苯并-15-冠-5的合成及其对
A cyclopropenyl aluminum deriv
Reactions of CpArCHCHArCp with
苯基修饰(-环糊精的自组装行为
Mechanism of NO transfer from
Polyrotaxane with cyclodextrin
Unexpected reactivity of CH(3,
Cation-controlled aqueous disp
Isolation of new disilanylene-
Synthesis of bridged and metal
Synthesis and application of c
Synthesis and structures of 1,
Enantioselecitive Rh-catalyzed
Multi[2]rotaxanes with gold na
Diastereomeric molecular recog
Synthesis of HC[(Ct-Bu)2(NAr)2
Reactions of Si-H-functionaliz
Reactivity of four-membered he
Iodobenzene dichloride as a st
Diverse Conformation and Exten
Diffusion of single alkane mol
Ru-Catalyzed asymmetric hydrog
Selective binding and inverse
Mechanism and driving force of
Interlocked bis(polyrotaxane)
A general synthetic route to d
牛心朴子草抑制植物病毒活性成分安托芬的室内和田间活性测定
三氟乙酸和三氟化硼乙醚在硫杂卟啉合成中的应用
剪刀型双卟啉锌配合物在Cu^＋离子和DABCO双客体调控下的荧光开关效应
均苯三酰胺桥联三环糊精／Zn^2＋／金刚烷衍生物三元超分子体系的合成及其羧肽酶A模拟研究
三嗪基苯胺桥联双环糊精的合成及其对染料分子的选择键合
全甲基及其多胺修饰环糊精与牛血清白蛋白的相互作用
双吲哚基修饰杯[4]芳烃对Hg^2＋的比色传感行为
钾离子调控的1，5-萘基桥联双冠醚的”off-on—off”和”on-off-on”行为
Chiral pyrrolidine-azole conjugates： Simple and efficient asymmetric organocatalysts for Michael addition to nitrostyrenes
Dynamic Assemblies and Photophysical Changes of Zinc Porphyrin Dimer Regulated by N-Containing Ligands
Isolation of New Disilanylene-bridged Bis（cyclopentadienyl）tetracarbonyldiiron Complexes and Molecular Structure of [η^5, η^5-C5H4SiMe（SiMePh2）C5H4]Fe2（CO）2（μ-CO）2
An Environmentally Benign System for Synthesis of β-Hydroxylketones： L-Histidine Asymmetrically Catalyzed Direct Aldol Reactions in Aqueous Micelle and Water-like Media
牛心朴子草中生物碱的抑制植物病毒活性研究
Asymmetric Synthesis of Bicycl
Rapid palladium-catalyzed cros
L-Prolinamide Catalyzed Aqueou
An Environmentally Benign Syst
Pyrrolidine as an efficient or
丁酮与硝基苯甲醛反应生成的aldol产物的NMR表征方法及其应用
An Environmentally Benign System for Synthesis of β-Hydroxylketones： L-Histidine Asymmetrically Catalyzed Direct Aldol Reactions in Aqueous Micelle and Water-like Media
高性能有机氟硅改性丙烯酸酯乳液的研究
无溶剂条件下脯氨酸甲酯催化syn选择性羟醛缩合反应
期刊信息
  • 《中国化学：英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编：
  • 地址：上海市枫林路354号中科院上海有机化学研究所
  • 邮编：200032
  • 邮箱：
  • 电话：021-54925243
  • 国际标准刊号：ISSN：1001-604X
  • 国内统一刊号：ISSN：31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,荷兰文摘与引文数据库,美国科学引文索引（扩展库）,日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175