番茄红素是一种良好的抗氧剂,能减小活性氧自由基对细胞的氧化损伤、预防癌症、降低血液中胆固醇水平、预防心脑血管疾病,已被广泛应用于食品添加剂、化妆品和医药领域,市场前景良好。该文综述了用重组大肠杆菌和三孢布拉霉菌体发酵生产天然高品质番茄红素的研究现状,并对用微生物发酵生产番茄红素的前景作出展望。
Lycopene is a good antioxidant, which could reduce the oxidative damage of reactive oxygen radicals on cells. Lycopene can lower cholesterol level in blood, prevent cancer and cardiovascular diseases, and it was widely used in the fields of food additives, cosmetics and medicine, which showed good market prospects. In this paper, the status of fermentation production of natural lycopene by recombinant Escherichia coli and Blakeslea thspora was reviewed, and the potential production of lycopene by microbial fermentation was also prospected.