中文摘要：

目的探讨血清降钙素原检测结果在下呼吸道感染患儿治疗中的应用及效果。方法选择2012年8月至2013年3月住院治疗的200例下呼吸道感染患儿为研究对象。随机分为两组,即标准抗生素治疗组（对照组）和降钙素原指导下抗生素治疗组（降钙原组）,各100例,比较观察两组患儿临床症状和体征消失时间、住院时间、住院费用、治疗疗效、抗生素使用率和使用时间、抗生素费用。结果降钙原组患儿治疗总有效率、临床症状和体征消失时间与对照组比较差异无统计学意义（P〉0.05）,但是,降钙原组抗生素使用率和使用时间及费用、住院时间和费用均明显低于对照组,两组比较差异有显著性（P〈0.05）。结论在血清降钙素原检测结果指导下治疗下呼吸道感染患儿能够明显减少患儿住院时间、住院费用,降低抗生素使用率,减少抗生素使用时间。

英文摘要：

Objective To investigate the application and result of procalcitonin detection in children with lower respiratory tract infection.Methods Two hundred lower respiratory tract infection children treated in the Department of Pediatrics of our hospital from August 2012 to March 2013 were divided into standard antibiotic treatment group（control group,n = 100） and serum procalcitonin-based antibiotic treatment group（procalcitonin group,n =100）.The disappeared time of symptoms and signs,length and cost of hospitalization,treatment efficacy,usage rate,length and cost of antibiotics treatment were compared between two groups.Results There were no significant differences in the total effective rate and disappeared time of symptoms and signs between two groups（P 0.05）.However,the length and cost of hospitalization,usage rate and length of antibiotics treatment,and antibiotic charges were all lower in serum procalcitonin-based antibiotic treatment group than those in the control group（all P 0.05）.Conclusion Serum procalcitonin-based treatment for children with lower respiratory tract infection can significantly reduce the length and cost of hospitalization,and usage rate,length and cost of antibiotics treatment.