中文摘要：

目的观察大肠癌围手术期患者中医证候分布及动态变化规律,为中医药干预提供证候学依据。方法对228例大肠癌手术患者进行临床调查,观察手术前后临床症状、舌象、中医辨证及证候变化。结果大肠癌患者术前以气血瘀滞证（34.2%）和湿热蕴结证（28.9%）两类实证为主；术后早期（术后1周）虚性证候明显增加,主要为气血两虚证（17.1%）；术后中期（术后1个月）呈现虚实夹杂之象；术后晚期（术后3个月）虚证比例逐渐降低；结论大肠癌患者围手术期中医证候演变呈现一定规律,大肠癌围手术期的中医药治疗可遵循这一规律。

英文摘要：

Objective To observe the changes of TCM syndromes of colorectal cancer patients before and after surgery,in order to guide the TCM treatment. Methods Two hundred and twenty-eight patients with colorectal cancer were enrolled. Their signs and symptoms,tongue picture,and differentiated TCM syndromes before and after surgery were compared. Results The preoperative TCM syndromes were characterized by excess such as qi stagna-tion and blood stasis （34.2%） and accumulation of damp-heat （28.9%）. In the early stage after surgery （no more than one week）,the deficient syndromes gradually increased,with the syndrome of qi-blood deficiency accounting for 17.1%;in the middle stage after surgery （one month）,a phenomenon of combined excess and deficiency syn-dromes presented;in the later stage of postoperation（3 months）,the deficient syndromes decreased. Conclusion The evolution of perioperative TCM syndromes in patients with colorectal cancer may follow certain patterns. This may be of value in guidance of adjuvant TCM treatments of colorectal cancer.