中文摘要：

研究简单且高灵敏度的检测广谱抗癌药物顺铂（cis—Pt）的新方法在临床上具有重要意义．无机纳米粒子由于具有特殊的光（电）学性质以及其它与形状或粒径有关的性质，近十年来已被广泛应用于各种生物分析和生物医学检测技术中．

英文摘要：

A novel method of colorimetric assay for determining cis-Pt （cis-diammino-dichloroplatinum Ⅱ ） was found by the binding affinities between cis-Pt and DNA based on the change of surface plasmon resonance band of gold nanoparticles. The red-shift of the maximum band of the surface plasmon resonance band of gold nanoparticles increased linearly with the logarithm of the cis-Pt concentration from 40 to 2000 nmol/L and the detection limit is 40 nmol/L when the concentration of gold nanoparticles is 4 nmol/L. The colorimetric readout can be visualised with the naked eyes.