目的探讨Wilson病(Wilson disease,WD)患者是否存在眼区情绪认知障碍,了解基底节有无参与眼区情绪认知加工过程。方法将32例WD患者以及29名与其人口学资料相匹配的健康人(healthy control,HC)作为被试,采用眼区的6种基本情绪(喜、惊、恐、悲、厌、怒)任务,对两组进行测试。结果与HC组比较,WD组在在眼区情绪认知任务对怒(17.53±1.39分,P〈0.05),恐(15.88±1.21分,P〈0.05)和厌(18.00±1.85分,P〈0.001)眼区情绪认知存在明显障碍;而对于喜、惊、悲的眼区情绪认知任务识别却无障碍(均P〉0.05)。结论WD患者存在明显的怒、恐及厌眼区情绪认知障碍,基底节可能参与眼区情绪认知任务的加工过程。
Objective To investigate whether there are emotion recognition disorders from eye region in patients with Wilson disease(WD) and to examine whether the basal ganglia is involved in processing perception of emotions from eye region.Method The study included 32 WD patients(WD group) and 29 healthy control people(HC group).All subjects were tested using six basic emotions(joy,surprise,fear,sadness,disgust and anger) of the eye area.Results Compared with HC group,WD group had obvious recognition barriers at anger(17.53 ± 1.39 points,P 0.05),fear(15.88 ± 1.21,P 0.05) and disgust(18.00 ± 1.85,P 0.001),but not at joy,surprise and sadness.Conclusions WD patients have emotion recognition disorders in which the basal ganglia may be involved.