中文摘要：

目的研究中国南海小月柳珊瑚Menella kanisa中的化学成分。方法应用正相硅胶、SephadexLH-20凝胶、半制备反相高效液相色谱法（RP—HPLC）等多种分离手段对小月柳珊瑚Menellakanisa的乙醚提取物进行分离纯化，根据现代波谱技术结合文献报道进行结构鉴定。结果和结论从南海小月柳珊瑚Menellakanisa中分离得到5个过氧化麦角甾，分别鉴定为：5a，8a-过氧化胆甾-6-烯-3p-醇（1）、（22E）-5a，8a-过氧化胆甾-6，22-二烯-3伊醇（2）、（22E，24R）-5a，8a-过氧化麦角甾-6，22-二烯-3J争醇（3）、5a，8a-过氧化麦角甾-6，24（28）-二烯-3p-醇（4）、24（E）-5a，8a-过氧化胆甾-24-乙基-6，24（28）-二烯-3伊醇（5）。这5个过氧化甾醇均为首次从该种珊瑚中分离得到。

英文摘要：

Objective To investigate the chemical components of gorgonian Menella kanisa collected from the South China Sea. Methods The Et20 extract of gorgonian Menella kanisa was purified by repeated column chromatography on silica gel, Sephadex LH-20, and reversed-phase high-performance liquid chromatography （RP-HPLC）. The structures of the obtained compounds were determined on the basis of spectroscopic analysis and compared with the reported data. Results and Conclusion Five 5a,8a-epidioxy sterols were isolated from gorgonian Menella kanisa collected from the South China Sea, and their structures were determined as ： 5a, 8a-epidioxy-cholest-6-en-3β-ol （1）, （ 22E）-5a, 8a-epidioxy-cholesta-6,22-dien-3β-ol （2）, （22E, 24R ）-5a, 8a-epidioxy-24-methyl-cholesta-6, 22-dien-3fl-ol （ 3 ）, 5a, 8a-epidioxy-24-methyl-cholesta-6, 24 （ 28 ）-dien-3fl-ol （4）, （24E）-Sa,8a-epidioxy-24-ethyl-cholesta-6,24（28）-dien-3fl-ol （5）. All the five epidioxy sterols have been separated from the title Menella kanisa for the first time.