DELLA属于GRAS核转录调节因子家族,负向调节GA信号途径,并抑制植物生长发育。GA与其受体结合后,与DELLA蛋白发生互作,并通过26S蛋白酶体将DELLA降解,从而解除DELLA对植物发育的抑制作用。DELLA通过与不同的转录因子互作,调控下游基因的表达。文章综述了DELLA蛋白在GA信号传导中作用的分子机理和DELLA蛋白调控植物生长发育的功能,以及作为整合因子,DELLA在介导低温、光等环境因子及其它植物激素之间的交互作用的分子机制,并介绍了大豆DELLA功能的研究进展。
DELLAs belong to the GRAS transcriptional repressors and act as negative regulators in gibberellin signaling pathway to repress GA-mediated growth.GA derepress the inhibition of DELLA by forming GA-GA receptor-DELLA complex,leading to the destabilization of the DELLA protein via 26S proteasome pathway.DELLAs interact with various transcriptional factors to regulate the downstream gene expression.This article highlighted recent advances in our understanding of the molecular mechanisms of DELLAs' role in GA signaling and plant growth and development,and the integrator role DELLAs play between the GA pathway,other hormone-signaling pathways and environmental cues,as well as the researches of DELLA function in soybean.