中文摘要：

辣椒素是一种香草酰胺类生物碱,是从辣椒中获取的活性物质,近年的国内外研究表明辣椒素具有降糖降脂的功效。本文综述了辣椒素通过与辣椒素受体结合、调节褐色脂肪组织和白色脂肪组织、释放脂肪细胞因子、改变肠道菌群结构、调节饮食和肌肉组织功能等几种途径发挥降糖降脂作用的机理,以期为辣椒素作为降糖降脂药物或者保健产品的开发利用提供参考依据。

英文摘要：

Capsaicin is a vanilla amides alkaloid which is an active ingredient in chili peppers. Much recent research has demonstrated the hypoglycemic and hypolipidemic activity of capsaicin. This paper reviews recent progress in the research on the hypoglycemic and hypolipidemic mechanisms of capsaicin involving binding to the capsaicin receptor, adjusting the brown adipose tissue and white adipose tissue, releasing adipose cytokines,altering the gut microbial composition, modulating food intake and muscle performance, aiming at providing references for further development and applications of capsaicin as an ingredient of drugs or health products.