中文摘要：

浙贝母（Fritillariae thunbergii Bulbus）是一种常用的化痰止咳中药,为浙江著名的＂浙八味＂之一。硫熏能够使浙贝母增白、防虫蛀以及延长保质期,然而过度的硫熏不仅会影响浙贝母的品质,还会危害人体健康。因此,进行硫熏浙贝母的无损鉴别分析有利于浙贝母的品质监测,保障中药质量。采用近红外光谱结合化学计量学方法进行六种不同硫熏程度浙贝母的鉴别分析,在近红外（900-1 700nm）光谱条件下,采用＂boxplot＂统计分析1 000-1 100nm内样本间的光谱反射值的差异。同时采用主成分分析（PCA）进行六种样本的聚类分析。应用连续投影法（SPA）进行数据挖掘获得10条特征波段,建立其偏最小二乘判别分析（PLS-DA）模型。结果表明,建立的PLS-DA模型可达到与全谱类似的判别结果。近红外光谱技术结合化学计量学方法能够实现不同硫熏程度浙贝母的无损鉴别分析,这为后续进行硫熏浙贝母品质分析以及研发相应贝母便携检测仪提供参考。

英文摘要：

Fritillariae thunbergii Bulbus,as one of the famous ＂Zhe Ba Wei＂,is often used as expectorant and antitussive medicine.Sulfur fumigation is commonly good for whitening,mothproofing and extending the shelf-life of medicines.However,excessive sulfur fumigation will affect the quality of traditional Chinese medicines,even damage human health.Therefore,using non-destructive detection method of Fritillariae thunbergii Bulbus with sulfur fumigation is beneficial to monitor the quality of traditional Chinese medicines.This paper used near infrared spectroscopy（NIR）（900-1 700nm）combined with chemometrics to detect the Fritillariae thunbergii Bulbus fumigated with different concentrations of sulphur.＂Boxplot＂was adopted to analyze the difference among the samples in the range of 1 000-1 100 nm.Principal component analysis（PCA）was also used to cluster analysis of six different samples.Then successive projection algorithm（SPA）was applied to extract ten different characteristic wavelengths and establish the partial least squares-discriminant analysis（PLS-DA）models.Results showed that PLS-DA model had the similar results with full spectra analysis.Furthermore,NIR combined with chemometrics can be used to analyze the Fritillariae thunbergii Bulbus fumigated with different concentrations of sulphur.It provided a theoretical reference for the analysis of the quality of Fritillariae thunbergii Bulbus and the design of the portable instruments.