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中文摘要：
DNA编码序列的设计是影响DNA计算可靠性的重要途径,从DNA编码应满足的多约束条件中选取适当的约束条件,针对这些约束条件提出每个DNA个体应满足的评估公式以及目标序列集合的评价函数,采用文化进化粒子群算法解决DNA序列设计的多目标优化问题,仿真结果表明该混合算法针对DNA序列设计问题,在求解最优值能力,解的稳定性方面都取得了不错的效果。
英文摘要：
DNA sequence design is important way to influence reliability of DNA computing.Proper constrained items which DNA sequence should satisfy are selected,and then the evaluation formulas for each DNA individual and DNA sequence corresponding to the selected constrained terms are formulated.Cultural Evolution based Particle Swarm Optimization algorithm （CE-PSO） is proposed to solve the multi-objective optimization problem designed by DNA sequence.Simulation indicates that the hybrid algorithm does well on searching efficiency and key stability for DNA sequence design problem.
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