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补益类中药抗衰老活性成分研究概况
  • ISSN号:1674-070X
  • 期刊名称:《湖南中医药大学学报》
  • 时间:0
  • 分类:R285[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]中国医学科学院协和医学院神经科学中心药物研究所,北京100050, [2]湖南中医药大学,湖南长沙410208, [3]湘潭市中心医院,湖南湘潭411100
  • 相关基金:国家自然科学基金项目(81274122,81373997,81273629,81473570); 国家“重大新药创制”科技重大专项(2012ZX09301002-004,2012ZX09103101-006); 教育部长江学者和创新团队发展计划(PCSIRT)(IRT1007);教育部博士点基金重点项目(20121106130001); 北京市自然科学基金(7131013,7142115); 新药作用机制研究与药效评价北京市重点实验室资助项目(BZ0150).
中文摘要:

补益类药物根据其功效和中药适应症的不同可以分为补气药、补阴药、补血药和补阳药四类。本文以补益类中药的抗衰老作用为切入点,对补益类中药起抗衰老作用的相关主要有效成分进行总结,发现补益类中药的抗衰老有效成分主要是多糖类和皂苷类。目前已有部分多糖与皂苷在临床中使用效果明显,加之补益类中药具有资源丰富、品种繁多、成本低廉、毒副作用小等特点,因此相关补益类中药多糖成分与皂苷类成分产品值得进一步开发;可利用我国独特的中药资源优势,全面推进我国中药的产业化、现代化进程。

英文摘要:

Aging is the physiological changes caused by the aging of the tissues and organs, and it is the comprehensive performance of various functional decline of the organism. There are kinds of theories about aging, but the exact mechanism is still unknown. Tonic Chinese medicine, also known as the tonic Xu or Yang Chinese medicine, refers to complement of Yin and Yang deficiency of vital energy, improve heart function, enhanced physique, improve the ability to resist disease, eliminate the deficiency syndrome. Modern pharmacology study shows that it can strengthen the body's immune function, improve the body's adaptability, promote metabolism, nourish Yin and strong, and so on. Tonic Chinese medicine according to its efficacy and indications of different Chinese traditional medicine can be divided into nourishing Qi, Yin,blood and Yang tonic medicines taking four classes. Taking the anti-aging effect of tonic Chinese medicine as the breakthrough point, to summarize the main effective components of tonic Chinese medicine which have anti-aging effects,eventually found relatively the anti-aging effective components of tonic Chinese medicine is mainly of polysaccharide and saponins classes. Now there are some kinds of polysaccharide and saponins which have obvious effects in clinical use, and tonic Chinese medicine has rich resources, wide variety, low cost, low toxicity, etc, so the related ingredients like saponin and polysaccharide components of tonic Chinese medicine products are worthy of further development, take advantage of our unique traditional Chinese medicine resources, promoting the industrialization and modernization of Chinese medicine in our country.

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期刊信息
  • 《湖南中医药大学学报》
  • 中国科技核心期刊
  • 主管单位:湖南省教育厅
  • 主办单位:湖南中医大学
  • 主编:黄惠勇
  • 地址:湖南长沙岳麓区含浦科教园区学士路300号湖南中医药大学含浦校区
  • 邮编:410208
  • 邮箱:xuebaotcm@126.com
  • 电话:0731-88458339 88458340
  • 国际标准刊号:ISSN:1674-070X
  • 国内统一刊号:ISSN:43-1472/R
  • 邮发代号:42-64
  • 获奖情况:
  • 2004,2006,2008年连续三次荣获全国高校两年评比一...,2005年被评为湖南省十佳科技期刊,连续三次被评为全国高校优秀自然科学学报,2009年全国高校科技期刊编辑质量优秀奖,2011年荣获湖南省新闻出版局"第五届十佳科技期刊"称号
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊
  • 被引量:10690