中文摘要：

目的 利用模型探讨99TcmO4-与18F- 氟脱氧葡萄糖（FDG）在图像采集中的相互影响，讨论同一患者是否可以同日分别采用 PET/CT 及 SPECT 两种仪器行高低两种能量放射性核素显像。材料与方法 利用统一规格、相同容积（500ml）的 5 个塑料瓶（编号 A、B、C、D、E），其内均注入 500ml 蒸馏水制作成模型。A 瓶注入 0.5mCi18F-FDG 行 PET/CT 显像；B 瓶注入 1mCi99TcmO4-行 SPECT 显像；C 瓶内同时注入混合好的0.5mCi18F-FDG 和 1mCi99TcmO4-；D 瓶内先注入 1mCi99TcmO4-后再注入 0.5mCi18F-FDG ；E 瓶先注入0.5mCi18F-FDG 后再注入 1mCi99TcmO4-。然后对 C、D、E 瓶分别行 PET/CT 显像和 SPECT 显像，并判断图像效果。结果 A 瓶 PET/CT 显像和 B 瓶 SPECT显像图像效果为 1 级；C、D 瓶 SPECT 及 PET/CT 显像图像均为 2 级；E 瓶SPECT 显像图像为 3 级，PET/CT 显像图像为 1 级。结论 同时加入18F-FDG和99TcmO4-对 PET/CT 和 SPECT 图像质量均有影响。先加入18F-FDG 后加入99TcmO4-对 PET/CT 图像质量影响小，但 SPECT 图像不能分辨。先加入99TcmO4-后加入18F-FDG 对 PET/CT 和 SPECT 图像质量均有影响。

英文摘要：

Purpose To evaluate interaction between 99 Tc m O 4-and 18 F-FDG in the image acquisition,and to discuss if the patient is eligible to perform radionuclide imaging with high-energy and low-energy by SPECT and PET/CT respectively on the same day.Materials and Methods The cardiac models were made by 5 plastic bottles with uniform specification and the same volume （500 ml）.All the bottles were filled in 500 ml water and numbered A,B,C,D and E,respectively.18 F-FDG was added to bottle A and performed PET/CT.99 Tc m O 4-was added to bottle B and performed SPECT.Mixed 0.5mCi 18 F-FDG and 1mCi 99 Tc m O 4-was added to bottle C,and for bottle D,1mCi 99 Tc m O 4-was added first and followed by 0.5mCi 18 F-FDG.For bottle E,0.5mCi 18 F-FDG was added first and followed by 1mCi 99 Tc m O 4-.Then all of C,D,E bottles performed PET/CT and SPECT imaging respectively,and the grades of images were evaluated.Results PET/CT imaging quality were grade Ⅰ for bottle A and SPECT imaging quality were gradeⅠfor bottle B.Both of PET /CT and SPECT imaging quality were grade Ⅱ for bottle C and bottle D.SPECT imaging quality were grade Ⅲ,and PET /CT images quality were grade Ⅰ for bottle E.Conclusion If 99 Tc m O 4-and 18 F-FDG are adding at the same time,both image quality of PET/CT and SPECT will be reduced.If 18 F-FDG is adding first and followed by 99 Tc m O 4-,PET /CT image quality will be slightly reduced,but SPECT images cannot be distingushed.If 99 Tc m O 4-is adding first and followed by 18 F-FDG,both PET /CT and SPECT imaging quality will be reduced.