目的通过分析脑性瘫痪( CP)患儿磁共振表现与其类型、粗大运动功能分级( GMFCS)及出生胎龄的关系,探讨MRI在小儿CP临床诊断中的价值。方法收集143例CP患儿的临床和MRI资料,回顾性分析其间相关性。结果MRI表现为室周白质损伤(PWMI)52例,弥漫性脑损伤31例,脑发育异常19例,局灶性脑血管意外11例,正常24例,无法分类性病变6例。不同类型MRI表现的GMFCS分布差异有统计学意义(χ2=87.974,P =0.000, Fisher 精确检验)。 PWMI的患儿中,早产儿多见,且主要为双瘫及偏瘫, GMFCSⅠ-Ⅲ级较多。弥漫性脑损伤中,四肢瘫及不随意运动型常见,GMFCS多为重度障碍。脑发育异常及局灶性脑血管意外足月儿多见,GMFCS显示为前者重度障碍多见,后者轻度障碍多见。结论 CP患儿MRI表现与CP类型、GM-FCS、出生胎龄有密切关系,对CP的早期诊断及预后评估有重要价值。
Objective To explore the valuation of MRI in clinic diagnosis of children cerebral palsy( CP) by tes-ting relationships between types of CP, gross motor function( GMFCS) ,gestational age at birth and MRI findings of the brain. Methods The clinic and MRI data were collected and their correlations were analyzed. Results A-mong 143 cases of cerebral palsy,52 cases were periventricular white matter injury( PWMI) ,31 cases were diffusive encephalopathy,19 cases were brain malformations,11 cases were focal cerebral vascular accident,24 cases were normal and 6 cases were unclassifiable. Distributions of GMFCS were significantly different among various neuroim-aging findings(χ2 =87.974,P=0.000,Fisher exact test). For PWMI, preterm infants were mainly involved with spastic diplegia or spastic hemiplegia, and GMFCS levels wereⅠ-Ⅲ. Diffusive encephalopathy was most com-monly shown in dyskinetic CP and spastic quadriplegia,and GMFCS levels were Ⅳ-Ⅴ. Brain malformations and focal cerebral vascular accident were common in term infant patients, and for GMFCS levels the former were Ⅳ-Ⅴ,while the latter wereⅠ-II. Conclusion Correlations are significant between MRI findings with types of CP, gross motor function and gestational age at birth and it's important for MRI in earlier diagnosis and prognosis valua-tion of cerebral palsy.