欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
人参皂苷是人参的有效化学成分,其中人参皂苷Rg3因具有显著的生理活性而备受关注。运用拉曼光谱的方法,对人参皂苷Rg3的两种异构体20-（R）-Rg3和20-（S）-Rg3进行了测量和分析。因20位羟基空间位置不同,20-（R）-Rg3与20-（S）-Rg3相比,归属于亚甲基的振动峰发生了明显的变化,表明两种异构体的堆积方式不同。归属于C=C振动的1674cm^-1峰的强度明显降低,表明在20-（S）-Rg3中,C27和C28较20-（R）-Rg3处于分子内部。对比拉曼光谱还发现,这一对异构体中糖环的空间结构基本相同。两种异构体拉曼光谱的明显差异,使得拉曼光谱技术成为鉴别人参皂苷Rg3异构体的一种快速、简便的分析方法。
英文摘要：
Ginsenoside Rg3,discovered from Red Panax ginseng,is a new anticancer agent,which shows inhibitive activities of tumor metastasis in mice and in vitro tumor cell invasion.There are two isomers for ginsenoside Rg3：20-（R）-Rg3 and 20-（S）-Rg3.The research on the Rg3 structure is limitted,with no report on the use of Raman spectroscopy in such molecules.In the present article,the authors employed the Raman spectroscopy to study the structure of ginsenoside Rg3.Compared with 20-（R）-Rg3,the hydrocarbon chain of 20-（S）-Rg3 is located in the inner of molecules.In addition,there are significant differences in band location and relative intensity between the spectra of 20-（R）-Rg3 and 20-（S）-Rg3,and this indicates that Raman spectroscopy can be used as a simple,fast and accurate analytical tool to identify ginsenoside Rg3 isomers.
同期刊论文项目
同项目期刊论文
Spectroscopy of 4,4 '-azopyridine by density functional theory and surface-enhanced Raman scattering
Analytical technique for label-free multi-protein detection-based on Western blot and surface-enhanc
Fluorescein isothiocyanate linked immunoabsorbent assay based on surface-enhanced resonance Raman sc
Simplified protocol for detection of protein-ligand interactions via surface-enhanced resonance Rama
SERS-active Ag substrate from the photo-active decomposition of electrodeposited divalent silver oxi
Nanoparticle metal - Semiconductor charge transfer in ZnO/PATP/Ag assemblies by surface-enhanced Ram
Direct Observation of Enhanced Raman Scattering for Molecules Adsorbed on TiO2 nanoparticles: Charge
Density functional theory and two-dimensional correlation polarized infrared spectroscopy studies on
Contribution of ZnO to Charge-Transfer Induced Surface-Enhanced Raman Scattering in Au/ZnO/PATP Asse
Deposition of Ag nanoparticles on porous anodic alumina for surface enhanced Raman scattering substr
Density functional theory calculation of vibrational spectroscopy of trans-1,2-bis(4-pyridyl)-ethyle
Silver microflowers and large spherical particles: Controlled preparation and their wetting properti
Preparation of zinc oxide nanostructure thin films via chemical vapour deposition and its SERS activ
Surface-enhanced raman scattering of 4-mercaptopyridine on the surface of TiO2 nanofibers coated wit
Surface-enhanced Raman spectroscopy and density functional theory study on 4,4 '-bipyridine molecule
Studies on the structure and miscibility of mixed Langmuir-Blodgett films of a double-armed dibenzo-
ZnO nanoparticle size-dependent excitation of surface Raman signal from adsorbed molecules: Observat
Enhanced Raman scattering as a probe for 4-mercaptopyridine surface-modified copper oxide nanocrysta
Facile fabrication of large area polystyrene colloidal crystal monolayer via surfactant-free Langmui
期刊信息
位置：