中文摘要：

合成了含有喹啉功能团的锌离子荧光探针，N′-（喹啉-2-亚甲基）-3-（-喹啉-2-亚甲基胺）苯甲酰肼（QQB），该探针与Zn^2＋结合后荧光发射光谱由405nm红移至510nm，且荧光强度增强，具有较高的检测灵敏度。生物体内含量较高的金属阳离子K^＋、Na^＋、Mg^2＋、Ca^2＋以及微量金属离子Mn^2＋、Co^2＋、Ni^2＋等对QQB-Zn^2＋的荧光强度无显著影响，表明QQB对锌离子具有较高的选择性。光谱滴定和ESI-MS谱表明QQB与Zn2＋以1：1的化学计量比形成配合物。

英文摘要：

（ E ）-N′-（ quinolin-2-ylmethylene ）-3-[ （ E ）-quinolin-2-ylmethyleneamino ]-benzohydrazide （ QQB）, as a chelating fluorophore, can detect Zn^2＋ selectively by shifting emission peak from 405 nm to 510 nm upon Zn^2＋ addition. Zinc binding not only makes the emission band red-shifts, but also enhances the fluorescence intensity. The probe is highly selective for Zn^2＋ over biologically relevant alkali metals, alkaline earth metals and the first row transition metals such as Mn^2＋ , Co^2＋ and Ni^2＋. Spectrophotometric titration and ESI-MS spectra indicate the formation of a 1 ： 1 complex of Zn^2＋ with QQB.