中文摘要：

dimyristoylphosphatidylcholine (DMPC ) 和最新孤立的 surfactin 类似物，[Asp1， Glu5 ] 在混合单层的 surfactin-C16 被学习。压力分子的区域等温线与原子力量显微镜学(AFM ) 相结合的表面被用来探查 DMPC 和 surfactin-C16 的界面的行为。结果证明在 DMPC 和 surfactin-C16 之间的可混和性依赖于臼齿的部分(x ) 和表面迫使的 surfactin。二个部件在纯水(pH=6 ) 上部分是能溶合的，显示那在那里存在什么时候 x 在二个部件之间的 0.5 个相互的相互作用。AFM 图象在 surfactin-C16 单层显示出类似的模式， DMPC/surfactin-C16 (XS=0.5 ) 混合了单层。把那 DMPC 基于发现它被相信将进在混合单层的 surfactin-C16 表面簇联合。而且，过量混合的免费精力(Gmex ) 被计算在混合单层在二个部件的可混和性上调查 subphase pH 的效果。Gmex 在碱的 subphase (pH=10 ) 上是否定的，这被发现什么时候 x 平等者到 0.75，显示在 surfactin 和 DMPC 之间的分子的相互作用以条件是吸引人的。这里介绍的结果建议在 surfactin-C16 和 DMPC 之间的恐水病的相互作用在相互的相互作用，和界面的活动起一个重要作用由 surfactin-C16 的极的组的电离状态被影响。

英文摘要：

The dimyristoylphosphatidylcholine （DMPC） and a newly isolated surfactin analogue, [Asp1, Glus] surfactin-C16 in mixed monolayer was studied. Surface pressure-molecular area isotherms combined with atomic force microscopy （AFM） were used to probe the interfacial behavior of DMPC and surfactin-C16. The results show that the miscibility between DMPC and surfactin-C 16 is dependent on surfactin molar fraction （Xs） and surface pressure The two components are partially miscible on pure water （pH= 6） when Xs is 0.5, indicating that there exists mutual interactions between two components. AFM images showed similar pattern in surfactin-C16 monolayer and DMPC/surfactin-C 16 （Xs = 0.5） mixed monolayer. Based on the finding it is believed that DMPC would coalescent into surfactin-C 16 surface clusters in the mixed monolayer. Furthermore, the excess free energy of mixing （△ G^（ex）m ） was calculated to investigate the effect of subphase pH on the miscibility of two components in the mixed monolayer. It is found that the △ G^（ex）m was negative on alkaline subphase （pH= 10） when Xs equals to 0.75, indicating the molecular interactions between surfactin and DMPC are attractive at the condition. The results presented here suggest that hydrophobic interactions between surfactin-C 16 and DMPC play an important role in mutual interactions, and the interfacial activity was influenced by the ionization state of polar groups of surfactin-C 16.