高血压患者,尤其是合并肥胖与糖脂代谢异常者,会存在一定程度的大血管病变。高血压是与代谢关系密切,且同时伴有血管损害的临床综合征。代谢性高血压血管病变机制复杂,临床上仅控制血压尚不足以有效减低心脑血管事件,建议早期及时控制多重代谢因素并进行危险性评估,依据循证医学证据选择治疗方法,干预策略应充分体现全面及个体化原则。
In recent years, studies have shown that many patients with hypertension have macroangiopathy, particularly in the obesity and metabolic abnormalities. Therefore, hypertension is a clinical syndrome which related with metabolism, and accompanied by vascular lesions. Mechanism of vasculopathy in metabolic hypertension is complex, so only the control of blood pressure is difficult to effectively reduce the cardiocerebral vascular events. We should control multiple metabolic factors early and timely and assess its risk, and choose the treatment methods based on evidence-based evidence.