目的:了解北京市区无偿献血者梅毒传染指标流行情况,为无偿献血的招募策略调整提供依据。方法分析2007年1月1日~2011月12月31日北京市红十字血液中心无偿献血者抗梅毒螺旋体的检测结果,按性别、年龄、职业、文化程度、献血方式、献血组织形式进行分层,回顾性调查分析各层5年间的整体情况。结果2007~2011年5年间北京市红十字血液中心1065177人次无偿献血者梅毒抗体筛查阳性者4923例,阳性率为0.462%;女性的阳性筛查率高于男性(χ2=27.84,P〈0.05);梅毒抗体阳性检出率随着年龄增长而增加,不同年龄层之间差异有统计学意义(P〈0.05);5种职业献血人群的阳性率间差异有统计学意义(P〈0.05),不合格率排序为农民〉其他〉工人〉职员〉学生;不同文化程度、不同献血形式以及不同献血组织形式献血人群的检测结果差异均有统计学意义(P 〈0.05),机采项目的抗梅毒螺旋体检测阳性率高于全血,高中以下人群和家庭互助人群的阳性率最高。结论献血者选择过程的质量控制是招募安全血源的重要环节,根据本地献血人群的特点,应选择低危的、具有较高文化程度的年轻人和学生,积极引导他们成为固定献血者。同时,提高检测效能进一步保证血液安全。
Objective To provide the basis for recruiting strategy adjustment by analyzing the epidemiological status of syphilis infection of unpaid blood donors in Beijing downtown. Methods Anti-TP test results of unpaid blood donors were analyzed and then hierarchical retrospective investigation were performed according to gender, age, occupation, edu-cational level, blood donation and organization way of blood donation on these results during 1 January 2007 to 31 De-cember 2011 in Beijing Red Cross Blood Center. Results 4923 cases of positive anti-TP were screened that accounted for 0.462% in all the 1 065 177 non-remunerated donors. Positive screening rate of female was more than male (χ2=27.84, P〈0.05);and it was grown with the increase of age gradually, which had statistically difference between differ-ent ages (P〈0.05);significant differences existed in the positive rate of five professional blood donation population (P〈0.05), they were farmers 〉 others 〉 workers 〉staff 〉 students in order; a statistically significant difference also existed in the positive rate of different"cultural levels donors" ,"donation type"and"blood donation organizations form" (P〈0.05); "under high school group" and "family replacement blood donation" won the top in apheresis. Conclusion Se-lecting low risk, high cultural level of young people and students and encourage them to become regular blood donors as far as possible should be scientific and effective recruitment strategies according to local blood donation population. At the same time, increasing the efficiency of blood screen can ensure the safety of blood in further.