目的:对新疆圆柏枝叶的化学成分进行研究。方法:采用硅胶、大孔吸附树脂和Sephadex LH-20等色谱方法进行分离,利用理化性质和波谱技术鉴定化合物结构。结果:分离纯化得到5个化合物,分别鉴定为:槲皮素-3-O-(6″-O-乙酰基)-β-D-吡喃葡萄糖苷(1)、海波拉亭-7-O-β-D-吡喃葡萄糖苷(2)、异槲皮苷(3)、4-表-松香酸(4)、β-谷甾醇(5)。结论:其中,化合物1~3为首次从该属植物中分离得到。
Objective: To isolate and determine chemical constituents from twig and leaf of Juniperus sabina. Methods: Five compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of the physicochemical properties and spectral analysis. Results: The structures were elucidated as quercetin-3-O-( 6″-O-acetyl)-β-D-glucopyranoside( 1),hypolaetin-7-O-β-D-glucopyranoside( 2),isoquercetin( 3),4-epi-abietic acid( 4),β-sitosterol( 5). Conclusion: Compounds 1 ~ 3 are obtained from Juniperus genus for the first time.