中文摘要：

目的探讨Ⅱ期结直肠癌根治术淋巴结检出数目与患者预后的关系。方法回顾性分析380例Ⅱ期结直肠癌患者的临床资料。结果本组术后5年内出现复发或转移的56例患者与无复发转移者平均淋巴结检出数分别为9．5枚／例和16．3枚／例（P〈0．01）．术后5年内死亡的97例患者与健在者平均淋巴结检出数分别为11．1枚／例和16．7枚／例（P〈0．01）．差异均有统计学意义。淋巴结检出大于或等于12枚／例组和小于12枚／例组的5年生存率分别为83．9％和62．0％（P〈O．01），复发转移率分别为6．4％和25．7％（P〈0．01），差异也均有统计学意义。单因素分析显示，Ⅱ期结直肠癌患者的预后与淋巴结检出数目有关（P〈0．05）。结论淋巴结检出数目多少影响Ⅱ期结直肠癌患者的预后．淋巴结检出数目多者复发转移率低．生存率较高。

英文摘要：

Objective To investigate the association between the number of retrieved lymph nodes and the prognosis of stage Ⅱ colorectal cancer. Methods Clinical data of 380 patients with stage Ⅱ coloreetal cancer were analyzed retrospectively. SPSS 13.0 was used for data processing. Survival rate was calculated by Kaplan-Meier method, and risk factors related to prognosis of stage Ⅱ colorectal cancer were analyzed by Logistic regression analysis. Recurrence rate and survival rate were assessed with Chi-squared test. Results The average number of lymph nodes retrieved from 56 patients who developed recurrence or metastasis in 5 year after surgery was 9.5, and 16.3 from patients who had no recurrence or no metastasis （P〈0.01）. The number retrieved from 97 patients who died in 5 years after surgery was 11.1, and 16.7 from survivors. Patients were divided into 2 groups： ≥ 12 group and 〈 12 group. The 5-year survival rate was 83.9% in 1〉 12 group and 62.0% in 〈 12 group, respectively （P〈0.01）, the recurrence rate was 6.4% in ≥12 group and 25.7% in 〈 12 group （P〈0.01）. The univariable analysis showed that the number of retrieved lymph nodes was significantly associated with the survival and recurrence in patients with stage Ⅱ colorectal cancer （P〈0.05）. Conclusions The number of retrieved lymph nodes is associated with the prognosis of stage Ⅱ colorectal cancer. Patients with more retrieved lymph nodes have a higher survival rate.