中文摘要：

丙酮醛缩二甲醇与氯乙烯格氏试剂反应得叔醇,然后经乙酐酰化制得1,2-二乙酰氧基-2-甲基-1-甲氧基-3-丁烯,进而水解得2-乙酰氧基-2-甲基-3-丁烯-1-醛,最后重排得到维生素A的关键中间体4-乙酰氧基-2-甲基-2-丁烯-1-醛,总收率约49%。

英文摘要：

4-Acetoxy-2-methyl-2-butenal, a key intermediate of vitamin A, was synthesized from methylglyoxal dimethyl acetal via condensation with chlorovinyl magnesium to give the corresponding tertiary alcohol, followed by acylation to afford 1,2-diacetoxy-2-methyl-l-methoxy-3-butene, which was subjected to hydrolysis and rearrangement with an overall yield of about 49 %.