中文摘要：

以2（或4）-氯间苯二酚和乙酰乙酸乙酯为原料，通过Pechmann缩合反应，合成了新的8（或6）-氯-7-羟基-4-甲基香豆素（1a或1b）；1经硫酸二甲酯甲基化得2a或2b；以四正丁基溴化铵作相转移催化剂，1经Williamson反应合成了6个新的氯代香豆素衍生物（3a-6a，3b，ab），产率66％～92％。1—6的结构经^1H NMR，IR和GC—MS表征。

英文摘要：

8 （ or 6） -Chloro-7-hydroxy-4-methylcoumarin（ la or lb） was prepared by Pechmann condensation between resorcinol chloride and ethyl acetoacetate. 1 reacted with dimethyl fulfate and produced 2a or 2b. Six new 7-alkylox-8 （or 6）-chloro-4-methyl coumarins （3a - 6a, 3b and 4b） in yields of 66% -92% were synthesized via Williamson reaction of 1 and alkyl halides using tetrabutylammonium bromide as a phase transfer catalyst. The structures of 1 - 6 were characterized by ^1H NMR, IR and GC-MS.