中文摘要：

为了获取手指运动过程中不同脑功能区之间的联系，以及这种功能性联系在时频域和空间的变化，记录了与手指运动相关的脑磁图信号，然后对其进行相干性分析，并计算了不同位置信号之间的相干性系数。通过时频分析进一步探讨了在α（5～15Hz）、β（16～25Hz）、lowγ（30—45Hz）3个频带的不同皮层区联系随时间的变化关系。结果表明：α、β、lowγ3个频带与所选参考信号相干性呈现出位置大致相同，相干强度和相干范围均从α到lowγ依次递减，相干性系数随时间而变化，进而推论出相干性的变化表明对侧运动皮层存在不同的神经模式，而且这些神经模式也是随时间变化的，由此反映出不同功能区的联系在时频域的变化。

英文摘要：

The present study was aimed at investigating the connection between spatially separated brain regions, as well as the changes of the connection in time and frequency domain. Self-paced finger press related magnetoencephalography signals were recorded and analyzed by means of coherence analysis. The coherence coefficient of two signals corresponding to different cortical areas was calculated. Time frequency analysis was also used to determine if the cortical connection changes closely co-vary with time over the course of motor task in the three frequency band- α（ 5-15 Hz） 、β（16-25 Hz） and low γ（ 30-45 Hz）. The results showed that channels with the most significant coherence relative to the selected reference channel were approximately in the same area, and with an increase of frequency band both the coherence coefficient and the coupled area declined. Moreover, the coherence coefficient changed co-varied with time in the three frequency band. It was infered that there are different neuronal modulations in the contralateral motor cortex, and this modulation co-varies with time, which consequently reflects the changes of correlation between different brain regions in time and frequency domain.