中文摘要：

目的：探讨川楝胶囊对经前期综合征肝气逆证猕猴模型表情行为及微观指标的影响。方法采用择时挤压造模法，并以放射免疫法和毛细管电泳法分别测定其血清及尿中激素、递质水平。结果川楝胶囊可显著改善模型猕猴表情行为异常，并对造模刺激所致模型猕猴雌二醇水平的下降和对泌乳素、5-羟色胺、去甲肾上腺素水平的上升起到一定的纠正与调节作用，使其恢复至接近正常水平。结论川楝胶囊对经前期综合征肝气逆证所引起的单胺类神经递质和性激素及其调节激素分泌紊乱有一定的治疗作用，这一发现为病证的临床药物干预提供了药效学实验依据。

英文摘要：

Objective To explore the effect on macaques＇ expression and behavior and microcosmic indexes of the liver-qi invasion in premenstrual syndrome treated with chuanlian capsule. Methods Observed the changes of macaque models＇ expression and behavior through immobilizing in luteal phase and detected neurotransmitter changes in serum and urine with capillary electrophoresis, hormone changes in serum and urine with radio-immunity. Results Macaques＇ expression and behavior changes, the decrease of estradiol （E2）, the increase of prolactin （PRL）, norepinephrine （NE） and serotonin were rectified and regulated by chuanlian capsule. Conclusion Chuanlian capsule can treat neuro-endocrine disorder caused by premenstrual syndrome liver-qi invasion, which provides pharmacodynamic test evidence for clinical treatment.