微囊藻毒素(MCs)是由蓝绿藻类产生的一种强烈的环状七肽肝毒素。其对水体的污染已成为全球关注的问题。面对MCs引起的健康危害和潜在的经济损失,研究有效对抗MCs的化学保护剂具有重要的现实意义。该文就国内外对抗MCs毒性的相关化学保护剂(水飞蓟素、姜黄素、绿茶多酚、环孢素A、利福平和微量元素补充剂)等的研究进展进行综述。
Microcystins (MCs) is a potent cyclic heptapeptide hepatotoxin produced by the blue-green algae,Microcystis aeruginosa. The pollution caused by microcystins has become a global concern. Facing to MCs-induced health hazards and potential economic losses, it has an important practical significance to study the effective chemoprotectants against MCs. In this paper, both domestic and abroad researches on the chemoprotectants (silymarin,curcumin, green tea polyphenols, cyclosporin-A, rifampin, trace element supplementation) against MCs were reviewed.