中文摘要：

目的 调查我院老年心血管内科患者门诊用药情况。方法 采用整群抽样的方法,入选2013年11月在我院老年心血管内科就诊的患者523例,分析门诊930张处方中的心血管疾病诊断及用药情况。结果 老年心内科就诊的患者平均年龄（77.35±10.14）岁,平均诊断疾病（2.50±0.91）种/人,同时诊断3种疾病者占47.6%。疾病诊断前3位是血脂异常、高血压和冠心病。人均处方用药（4.98±2.31）种,联合用药≥5种者占总调查人数的39.96%。其中,高频处方药物为抗血小板药、他汀类调脂药和钙离子拮抗剂。单病种用药分析显示,高血压联合用药方案与指南推荐略有差异,冠心病或血脂异常处方用药基本符合二级预防要求。非治疗性用药,如维生素、钙片及活血化瘀类中成药处方占总用药的9.3%。结论 老年心血管内科门诊患者同时患多种疾病、联合用药者多见,门诊处方基本符合疾病的循证推荐方案,但与指南仍有一定差距,且存在非治疗用药比例偏高等不合理用药倾向。

英文摘要：

Objective To investigate the drugs used in elderly cardiovascular disease patients. Methods Nine hundred and thirty prescriptions for 523 elderly cardiovascular disease patients admitted to our department in November 2013 were analyzed. Results The mean age of the patients was 77.35 ± 10.14 years. The average number of diagnosed cardiovascular diseases in each patient was 2.50 ± 0.91. Those who were diagnosed with 3 cardiovascular diseases accounted for 47.6%. The top 3 diagnosed diseases were dyslipidemia, hypertension and coronary heart disease. The number of drugs used in prescriptions for each patient was 4.98 ± 2.31. The number of patients with their prescribed drugs ≥ 5 accounted for 39.96% of the investigated patients. The most frequently prescribed drugs were antiplatelet, statins and calcium channel blockers. The analysis of drugs used in treatment of a single disease showed that combined medication for hypertension was somewhat different from the recommended medication, while the prescriptions for coronary heart disease or hyperlipidemia could meet the requirement of their secondary prevention. The non- therapeutic drugs, such as vitamins, calcium tablets, blood circulation promoting and blood stasis removing herbals accounted for 9.3% of the totally used drugs. Conclusion Elderly outpatients suffer from several cardiovascular diseases and are usually treated with combined medications. Drugs prescribed in outpatient department accord with the evidence-based recommendation although they are somewhat different from those recommended in the guidelines and irrational use of drugs still exists.