中文摘要：

天然黄酮碳糖苷化合物特有的稳定性和显著的生物活性，使其化学合成成为当今糖化学领域的研究热点之-．本工作立体专一性地全合成了天然黄酮碳苷Parkinsonin B．通过控制物质的量比，首先高选择性合成了2-羟基-4，6-二甲氧基苯乙酮（3），并与糖给体O-（2，3，4，6-四-O-苄基-α—D-葡萄糖基）三氯乙酰亚胺酯（7）发生立体专一性糖基化反应得到碳糖苷化合物8，化合物8经查耳酮路线进而合成黄酮碳苷Parkinsonin B（1）．经IR，MS，^1H NMR及元素分析证实了产物及中间体的结构，同时讨论了全合成反应的主要影响因素，并对其^1H NMR解析进行了探讨．

英文摘要：

Owing to their special stability and prominent biological activity, C-glycosylflavones and their chemical synthesis have recently attracted considerable attention in the field of glycoscience. A total synthesis of glycosylflavone parkinsonin B with specific stereoselectivity is reported herein. 2-Hydroxy-4,6-bismethoxy acetophenone （3） was synthesized by one step in high regioselectivity under the optimal condition. The compound 3 was then glycosylated with O-（2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl） trichloroacetimidate （7） as active glycosyl donor with specific stereoselectivity to produce compound 8. Parkinsonin B （1） was synthesized by the chalcone route from compound 8. The structures of target compound 1 and intermediates were confirmed by IR, MS, ^1H NMR spectra and element analysis.