中文摘要：

背景：中药的某些成分有与生长因子类似的功能和相应的药理作用,对细胞增殖以及组织或器官的修复、再生等都具有重要的促进作用,且价格低廉,理化性质相对稳定,因此中药在组织工程中的应用越来越引起国内外研究者的广泛关注。目的：综述中药在干细胞增殖和组织工程中的应用。方法：以“中药,组织工程,干细胞,抗炎,交联,表面修饰,成骨细胞,血管”为中文检索词,以“the traditional Chinese medicine,tissue engineering,application,stem cell,anti-inflammatory,cross linking,surface modification,osteoblast,blood vessel”为英文检索词,由第一作者检索PubM ed数据库、中国知网1987至2015年间关于中药在干细胞增殖和组织工程中应用的文章。结果与结论：天然药物和传统中药有望成为生长因子和抗生素的替代物而应用于组织工程领域,其在组织工程中具有抗炎、表面修饰、促进血管生长、抗凝血、交联、促进干细胞增殖与分化等广泛的作用。

英文摘要：

BACKGROUND：Some Chinese herbal ingredients produce the analogical and pharmacological effects equivalent to growth factors, which can promote cel proliferation as wel as tissue and organ recovery and regeneration. Additional y, they possess low price and relative stable physicochemical property. Thus, the applications of traditional Chinese medicine in tissue engineering has attracted more attentions of researchers al over the world. OBJECTIVE：To review the application of the traditional Chinese medicine in stem cel proliferation and tissue engineering. METHODS：A computer-based retrieval of PubMed and CNKI databases was performed for articles concerning the application of traditional Chinese medicine in stem cel proliferation and tissue engineering published from 1978 to 2015. The keywords were“the traditional Chinese medicine, tissue engineering, application, stem cel , anti-inflammatory, cross linking, surface modification, osteoblast, blood vessel”in English and Chinese, respectively. RESULTS AND CONCLUSION：Natural medicine and the traditional Chinese medicine are expected to be applied in tissue engineering as a surrogate of growth factor and antibiotics, which exert anti-inflammatory, angiogenesis, surface modification, anticoagulation and cross-linking roles as wel as promote proliferation and differentiation of stem cel s in tissue engineering.