中文摘要：

目的：通过对1 125例儿童白癜风患者的临床特点和治疗进行总结,以期对白癜风的早期预防及治疗提供依据。方法：对1 125例第四军医大学西京医院皮肤科确诊的儿童白癜风病例进行回顾性分析。结果：1 125例白癜风患儿中,男女比1.04∶1,平均始发年龄7.03岁,发病年龄以5～9岁最多见（62.04%）,平均病程15.32月。227例（20.1%）有家族史,春夏季发病或病情加重者所占百分比高;15.29%患儿发病前有外伤、精神因素、日晒等诱因。临床表现以寻常型最常见（86.31%）,6.84%伴发其他疾病,其中晕痣最多,共50例（4.44%）,且伴发晕痣者平均发病年龄早于无合并晕痣者。治疗包括中医中药、局部或系统使用糖皮质激素、免疫调节剂、光疗法及外科手术等方法,以联合治疗为主,疗程1年有效率达54.93%。结论：家族史阳性、伴发晕痣、氧化应激损伤均是儿童白癜风发病的危险因素。儿童白癜风的治疗受限,疗效不理想,有待进一步探索。

英文摘要：

Objective To summarize and analyze the clinical characteristics and treatment of 1125 cases of children vitlligo,and to provide information for early prevention and proper treatment.Methods A retrospective study was conducted on 1 125 children vitiligo diagnosed at the Department of Dermatology in Xijing Hospital.Results Of the 1 125 children,the ratio of boys and girls was 1.04：1,with a mean onset age of 7.03 years.The most frequent age of onset was between 5 to 9 years（62.04%）.The mean duration of vitiligo was 15.32 months.Patients（12.09%） recalled family history of vitiligo.The onset or progression of disease usually occurred in summer and spring.15.29% patients had precipitating factors such as trauma,stress,and solarization.The most common type of vitiligo was vitiligo vulgaris（86.31%）,6.84% presented combined diseases,Halo nevi was present in 50（4.44%） cases,who revealed an earlier onset of vitiligo.The treatment of children vitiligo included traditional Chinese drug,topical or systemic corticosteroids,immunomodulator,phototherapy and surgical therapy,mainly in combination.54.93% children with vitiligo responded to treatment of one year.Conclusion The family vitiligo history,halo nevi association and oxidative stress are risk factors for vitiligo in children.Management is difficult as therapeutic options are restricted in children,desiring further research.