中文摘要：

目的分离鉴定藏药萨折中的单胺氧化酶抑制剂。方法运用硅胶、聚酰胺、凝胶柱色谱和HPLC分离纯化萨折的化学成分,并根据其理化性质和波谱数据鉴定化合物结构。采用Holt法进行抗单胺氧化酶活性测定。结果从萨折的乙醇提取物中分离得到3个化合物,分别鉴定为没食子酸（1）,没食子酸甲酯（2）,3,4,8,9,10-pentahydroxydibenzo[b,d]pyran-6-one（3）3个化合物。其对单胺氧化酶的半数抑制浓度（IC50）分别为10.0、35.9、35.2μmol/L。结论化合物3为首次从萨折中分离得到,化合物1-3均具有较强单胺氧化酶抑制活性,其中化合物1活性最好,其IC50为10.0μmol/L。

英文摘要：

AIM To study monoamine oxidase inhibitors from Syzygium cumini（ Linn.） Skeels. METHODS The compounds were isolated and purified by various column chromatographic techniques and their structures were elucidated on the basis of spectral analysis（ EI-MS,1H-NMR,13C-NMR）. RESULTS Three compounds were isolated and identified as gallic acid（ 1）,methyl gallate（ 2） and 3,4,8,9,10-pentahydroxydibenzo [b,d]pyran-6-one（ 3）. CONCLUSION Compound 3 is obtained from this plant for the first time. Compound 1 shows significant inhibitory activities against the monoamine oxidase with IC50 values of 10. 0 μmol / L.