目的 探讨右归胶囊对腺嘌呤致肾阳虚不育模型大鼠精液质量的影响.方法 以腺嘌呤灌胃SD大鼠,复制生精细胞损伤的肾阳虚不育大鼠模型,通过计算机辅助精子分析系统(CASA)观察右归胶囊对精子密度、活率、活力、及精子各项动态参数的影响.结果 右归胶囊能够显著改善大鼠精子密度水平、精子活率,a级、b级精子百分比,精子曲线运动速度、直线运动速度、平均路径速度、精子侧摆幅度,精子直线性、前向性百分比.结论 右归胶囊可明显改善肾阳虚不育模型大鼠的精液质量,提高其生育能力.
Objective To investigate the influence of Yougui Capsules on sperm quality in rat model of infertility (kidney yang deficiency) induced by adenine.Methods The rat model of infertility (kidney yang deficiency) with impaired spermatogenic cells was established through feeding adenine in SD rats.The influences of Yougui Capsules on sperm density,motility rate,vitality and different dynamic parameters were observed by using computer-assisted semen analysis system (CASA).Results Yougui Capsules significantly improved sperm density,sperm motility rate,percentages of A level and B level sperms,sperm curvilinear motion,sperm rectilinear motion,velocity of average pathway and VLH,and percentages of sperm linearity and forward motility.Conclusion Yougui Capsules can significantly improved the sperm quality and fertility in rats with infertility (kidney yang deficiency).