白细胞介素、干扰素、粒巨噬细胞集落刺激因子等细胞因子作为疫苗的免疫佐剂能增强机体的细胞和体液免疫应答,从而增强疫苗的特异性免疫反应,在细菌、病毒、寄生虫及肿瘤疫苗的研究中具有重要的作用。对细胞因子免疫佐剂的效应机制及其在兽医临床中的应用进展进行阐述,为细胞因子佐剂在兽医临床上的进一步应用提供参考。
Cytokines as immunoadjuvant could enhance cellular immunologic response and humoral immunoresponse of animals,thus enhance specific immunity response of vaccine.Cytokines had crucial role in bacterium,virus,parasite and tumor vaccine's researched.This cytokines include interleukin,interferon and granulocyte-macrophage colony-stimulating factor and so on.Recent advances were reviewed in the effective mechanisms and application of cytokines,which could provide important references for veterinary clinic application.