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中文摘要：
近年来,越来越多的证据表明阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与心血管疾病关系密切,在急性冠脉综合征患者中,睡眠呼吸暂停发病率高达69%。对于症状明显的OSAHS患者,持续气道正压通气（CPAP）是主要的治疗方法。多项研究发现,对OSAHS患者进行CPAP治疗,可以降低心肌需氧量和增加冠状动脉血流量,最终降低冠心病发病率。然而,CPAP治疗是否可以降低合并OSAHS的冠心病患者的主要不良心血管事件和主要不良脑血管事件,还有待进一步研究。本文就OSAHS与冠心病的发病机制、早期诊断、治疗等方面的相互影响予以综述。
英文摘要：
In recent years,increasingly more evidences suggest that obstructive sleep apnea hypopnea syndrome（ OSAHS） is closely related with cardiovascular disease. Among patients with acute coronary syndrome,the incidence of sleep apnea is as high as 69%. CPAP continues to be the primary therapy for patients with symptomatic OSAHS. Most studies report that the treatment of OSAHS with CPAP leads to a reduction in myocardial oxygen demand and an increase in coronary blow flow,eventually reduces the incidence of coronary heart disease. However,further studies are needed to determine definitively whether CPAP treatment reduces major adverse cardiovascular events（ MACE） and major adverse cerebrovascular events. The paper made a review on the interaction effect between OSAHS and the pathogenesis,early diagnosis and treatment of coronary heart disease.
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