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现代分析技术在中药质量评价中的应用

ISSN号：1674-1749
期刊名称：《环球中医药》
时间：0
分类：R284.1[医药卫生—中药学;医药卫生—中医学]
作者机构：[1]黑龙江中医药大学药学院,哈尔滨150040, [2]辽宁中医药大学针灸推拿学院, [3]山西仟源制药股份有限公司
相关基金：2014年哈尔滨应用技术研究与开发项目（2014RFQXJ1162）; 2013年度黑龙江中医药大学科研基金面上项目（201307,201316）

作者：南洋[1], 徐鹏[2], 丁宏[3], 刘莉莉[1], 董辉[1], 马薇薇[1]

关键词：分析仪器, 中药材, 色谱指纹图谱, 超高速液相, 液质联用, 气质联用, 多组分, Analytical instrumentation, Chinese herbal medicine, Chromatographic finger-printing, Ultra-performance liquid chromatography, Liquid chromatography coupled to mass spectrome-try, Gas Chromatograph coupled to Mass Spectrometry, Multi-component mixture

中文摘要：

中药在世界各地得到广泛使用,西方国家也逐渐选择中药作为辅助治疗的药物。然而,中药存在成分不明确等质量和安全问题,阻碍了中药在国际社会医疗保健中的应用与普及,这正是前沿的分析技术急需解决的关键问题,确保可重复识别和检验中药所含的化学成分。近年来技术先进的分析仪器不断研发,灵敏度和精确度得到明显的提高,可采用更高分辨率仪器分析多组分混合物,推动中药的质量控制标准朝着标准化方向进行。本文主要综述分析技术在中药材及其提取物质量监控和鉴定上的最新应用。

英文摘要：

Traditional Chinese medicine（ TCM） is widely used in all over the world,and moreand more western countries choose TCM as complementary therapy drugs. However,the quality,the safety and the unclear composition are important problems which as a hinder in the popularization and application of Chinese medicine in the international community health care area. These are the key problems to be resolved in the frontier of analysis technology. Repeatable identification chemical composition of TCM could be ensured. With improvements in engineering advanced analytical instruments in recent years,the sensitivity and accuracy have been improved obviously,which make the multicomponent mixture analyzed at a higher resolution,and promote the quality control of TCM toward standardization direction. This paper discusses the application of main analytical techniques in TCM,TCM formula and its extract on quality monitoring and evaluation.