载脂蛋白A-Ⅰ(apoA-Ⅰ)是高密度脂蛋白的主要结构蛋白之一。apoA-Ⅰ和动脉粥样硬化的负相关性已得到广泛的认同,对它们之间的关系已有了广泛而深入的研究。近年研究发现,apoA-Ⅰ和病毒感染之间也有很大相关性。此文综述了apoA-Ⅰ的基本结构、功能、在病毒感染中的作用,在其基础上,展望了apoA-Ⅰ的应用前景。
Apolipoprotein A-Ⅰ (apoA-Ⅰ) is the main structure protein of high-density lipoprotein. The negative con'elation between apoA-I and atherosclerosis has been widely recognized and has been in-depth researched. In addition, there are significant relations between apoA-Ⅰ and viral infection. This article deals with the structure, function of apoA-Ⅰ and its potential use in viral infection briefly.