设计合成了一系列新型含有噻唑和三唑环的亚胺类化合物,其结构经元素分析、^1HNMR和X射线晶体衍射确证.生物活性测试结果表明,部分化合物在50μg/L浓度下对苹果轮纹菌具有一定的杀菌活性.
In search of low toxicity and potent fungicide, 18 novel imine derivatives containing thiazole and trizole ring were synthesized. N-Substituted benzylidene-4- (4-chlorophenyl) -5- ( 1 H-1, 2,4-triazol-1 -yl) thiazol -2-amine were synthesized from the reaction of 4-(4-chlorophenyl)-5-( 1H-1,2,4-triazol-l-yl) thiazol-2-yl- amine and substituted benzaldehyde. The structures of the target compounds were confirmed by elemental analysis, ^1H NMR and X-ray diffraction. The bioassay results display that some of the tide compounds(6b, 6d, 6g, 6j, 6k) possess a fungicidal activity against P. piricola on test concentration(50 mg/L).