目的:了解基层医疗卫生机构中成药的应用情况及变化趋势,促进中成药的合理应用。方法:对上海市静安区3家基层医疗卫生机构2010-2012年中成药的种类、剂型、销售金额、用药频度(DDDs)和日均费用(DDC)等进行统计分析。结果:中成药销售金额及DDDs均呈上升趋势;≥60岁人群用药金额占87.21%;疾病频次排在前3位的依次为脑梗死、冠心病、高血压;在中成药各个类别中,活血祛瘀类销售金额占比约53%,稳居第1位;单品种销售金额排序居前列的中成药以口服制剂为主,DDDs排序居前3位的是银杏叶片、麝香保心丸和丹参片。结论:3家基层医疗卫生机构中成药使用基本合理。尚需加大对中药制剂的安全性研究和不良反应的监测力度,加强药学部门与临床科室的沟通,促进其优先选用安全、有效、经济的中成药,提高临床合理用药水平。
OBJECTIVE:To investigate the utilization and trend of Chinese patent medicines in grass-roots medical institutions of Shanghai Jing’an district. METHODS:The utilization of Chinese patent medicines in 3 grass-roots medical institutions of Shanghai Jing’an district during 2010-2012 was analyzed statistically in respects of type,dosage form,consumption sum,DDDs and DDC,etc. RESULTS:Both consumption sum and DDDs of Chinese patent medicines showed upward trends year by year. The consumption sum of the medicines for patients over 60 accounted for 87.21%;cerebral infarction,coronary heart disease and hypertension ranked the top three places in the list of frequency of disease. Of all categories of Chinese patent medicines,the blood-activating and stasis-dissolving medicines was sure to occupy the first place,the percentage of the consumption sum of which reached to53%;the oral medicines ranked forefront in the list of consumption sum,whereas Ginkgo leaf tablet,Shexiang baoxin pills and Danshen tablet ranked the top three places in the list of DDDs. CONCLUSIONS:The use of Chinese patent medicines in 3 medical institutions is rational on the whole. Great importance should be attached to safety study and ADR monitoring of TCM preparations,and the communication between pharmacy departments and clinical departments,as so to promote prior selection of safe,effective and economical Chinese patent medicine and rational use of medicine in the clinic.