中文摘要：

目的探讨剪切波弹性成像（SWE）及超微血管显像（SMI）技术在乳腺浸润性导管癌（IDC）病理组织学分级诊断中的应用价值。方法选取乳腺肿块患者60例，共64个病灶，均于术前行SWE及SMI检查，术后经病理证实为IDC，并依据病理结果进行病理组织学分级。SWE模式下记录病灶杨氏模量平均值（AveT1）及杨氏模量最大值（AveT2）；SMI模式下依据Adler分级标准评价病灶血流分级情况。分析比较IDC不同病理分级肿块的AveT1、AveT2及血流分级是否有差异。结果①IDC病灶病理组织学分级1级组AveT1平均值为（62．1±10．4）kPa，AveT2平均值为（93．0±20．1）kPa；2级组AveT1平均值为（79．8±8．6）kPa，AveT2平均值为（120．6±18．7）kPa；3级组AveT1平均值为（92．6±12．1）kPa，AveT2平均值为（137．3±21．5）kPa。AveT1及AveT2均随病理组织学分级的增高而呈增大，差异有统计学意义（P〈0．05）；②IDC病灶病理组织学分级1级组中，血流分级0-Ⅰ级者7个，Ⅱ-Ⅲ级者14个；2级组中，血流分级0-Ⅰ级者3个，Ⅱ-Ⅲ级者18个；3级组中，血流分级0-Ⅰ级者1个，Ⅱ-Ⅲ级者21个。病理组织学分级越高，血供丰富的肿块所占的比例就越大，差异有统计学意义（P〈0．05）。结论不同病理组织学分级乳腺肿块弹性特征及血流分级有差异，SWE及SMI技术对肿块病理组织学分级有初步提示作用，具有重要的临床应用价值。

英文摘要：

Objective To discuss the application value of shear wave elastography （SWE） and superb mierovaseular imaging （SMI） in pathological grading of breast invasive ductal carcinoma （IDC）. Methods Sixty patients with breast tumor were selected, which were totally 64 lesions. Before operation, SWE and SMI pattern were started to detect the lesions. And images in SWE and SMI pattern were saved. All lesions were proved to be IDC and pathological gradings were got according to the pathological result. The mean of Young＇s modulus（AveT1） and maximum of Young＇s modulus（AveT2） were recorded in SWE pattern, and degree of blood was recorded in SMI pattern followed Adler＇s grading standard. Then differences of AveT1, AveT2 and degree of blood in different pathological grading of invasive duetal carcinoma were evaluated. Results ①In pathological grading 1 group, the average of AveT1 was （62.1± 10.4）kPa, and the average of AveT2 was （93.0± 20.1）kPa. In pathological grading 2 group, the average of AveT1 was （79.8 ±8.6） kPa, and the average of AveT2 was （120.6± 18.7） kPa. In pathological grading 3 group, the average of AveT1 was （92.6 ± 12.1） kPa, and the average of AveT2 was （137.3 ± 21.5） kPa. The AveT1 and AveT2 were gradually growing with higher pathological grading of breast invasive duetal carcinoma, which were statistically significant （ P 〈0.05）. ②In pathological grading 1 group, there were 7 cases in the degree of blood 0 - Ⅰ and 14 in the degree of blood Ⅱ- Ⅲ. In pathological grading 2 group, there were 3 cases in the degree of blood 0- Ⅰ and 18 cases in the degree of bloodⅡ- Ⅲ. In pathological grading 3 group, therewere only 1 case in the degree of blood 0 - Ⅰ and 21 cases in the degree of blood Ⅱ- Ⅲ. There were more lesions of rich blood with higher pathological grading of breast invasive ductal carcinoma, which was statistically significant （ P〈0.05）. Conclusions There are differences of elastography and degree of blood in different