中文摘要：

谷氨酸是哺乳动物中枢神经系统兴奋性氨基酸神经递质，N-甲基-D-天冬氨酸（N—methyl—D-aspartate，NMDA）受体是谷氨酸重要的离子型受体。多种外周非神经组织也发现NMDA受体在维持组织正常的生理功能、参与组织细胞的损伤与修复等方面发挥重要作用。近年来发现在肺组织同样存在NMDA受体的表达，后者参与多种肺部疾病的发生与发展。

英文摘要：

Glutamate is a major excitatory neurotransmitter in the mammalian central nervous system （CNS）. N-methyl-D-aspartate receptor （NMDAR） is one of the most strongly implicated factors in excitotoxicity. The presence of NMDA-type glutamate receptors has been reported in non-neuronal tissues. Recent studies showed that NMDARs differentially express in lung, and participate in many kinds of pulmonary diseases.