中文摘要：

四溴双酚A（TBBPA）具有高效的阻燃效率和优越的热稳定性,被广泛用于各种电子电器产品、纺织品及建筑材料等,成为世界上使用量最大的阻燃剂。该文在综述国内外相关研究的基础上,依据TBBPA的不同暴露方式总结了经口、经皮肤和经呼吸暴露TBBPA的生物体代谢特征和毒性特征。TBBPA主要是通过粪便排泄,其次为尿液;TBBPA对哺乳动物的急性毒性较小,达到g/kg体重级的剂量才能引起毒性效应;慢性毒性主要表现为内分泌干扰性、肝肾毒性、神经毒性和免疫毒性等。

英文摘要：

Tetrabromobisphenol A （TBBPA） is widely used in the field of electronic and electrical products, textiles and building materials due to its efficient flame retarded efficiency and excellent thermal stability. This paper reviewed the organism metabolism and toxicity characteristics of TBBPA by oral, inhalational and dermal exposure, and the conclusion can be summarized that TBBPA was mainly excreted through the feces, followed by urine; TBBPA can cause toxic effect when the dose of TBBPA achieved g/kg body weight level; The chronic toxicity of TBBPA was mainly manifested in the endocrine disturbance, liver and kidney toxicity, neurotoxieity and immunotoxicity.