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Antifungal activities of matrine and oxymatrine and their synergetic effects with chlorthalonil
  • ISSN号:1007-662X
  • 期刊名称:《林业研究:英文版》
  • 时间:0
  • 分类:R978.5[医药卫生—药品;医药卫生—药学]
  • 作者机构:[1]College of Science, Nanfing University of Technology, Nanfing 210009, P. R. China, [2]College of Forest Resources and Environment, Nanjing Forestry University, Nanfing 210037, P. R. China
  • 相关基金:This work was supported by a project of National Natural Science Foundation of China (No. 30170776)
中文摘要:

三倍的妈和对五个森林病原菌类的 oxymatrine 的 EC_(50 ) 价值(镰刀霉 oxysporum, Valsa 品脱, Cladospo-rium oxysporum, Sphaeropsis sapinea, Marssoninabrunnea ) 被生物鉴定方法检验。结果表明了三倍的那个妈, oxymatrine 举办了强壮的禁止的活动到测试真菌的分生孢子萌芽。为禁止 Marssonina brunnea 的分生孢子萌芽的EC_( 50 )价值 ofmatrine , Cladosporium oxysporum , Sphaeropsis sapinea 是 123 μg ·m L~(-1), 272 μg ·m L~(-1), 1133 μg ·m L~(-1),分别地,并且EC_( 50 )为禁止镰刀霉 oxysporum 的分生孢子萌芽 oxymatrine 珍视, Sphaeropsis sapinea 是 532 μg ·m L~(-1), 601 μg ·m L~(-1),分别地。真菌的菌丝的生长被三倍的妈和 oxymatrine 显著地也禁止。EC_(50 ) matrineinhibiting 珍视 Sphaeropsis sapinea 的分生孢子萌芽, Valsa 大头针 i,镰刀霉 oxysporum 是 428 μ g · m L~(-1), 535 μ g · m L~(-1), 592 μ g · m L~(-1), 分别地。EC_(50 ) oxymatrineinhibiting 珍视 Valsa 大头针 i,的分生孢子萌芽镰刀霉 oxysporum 是 323, 618 μ g · m L~(-1),respectively。在合作测试, EC_(50 ) thiophanate 甲基(orchlorthalonil ) 和妈的混合物珍视三倍(或 oxymatrine ) 比 34 μ g · m L~ 低(-1) 当他们的 co-toxicitycoefficients 比 100 显著地高时。它显示碱和化学药品的混合在控制某些森林有潜在的实际利用真菌的疾病。

英文摘要:

The EC50 values of matrine and oxymatrine against five forest pathogenic fungi (Fusarium oxysporum, Valsa pini, Cladosporium oxysporum, Sphaeropsis sapinea, Marssonina brunnea) were examined by bioassay methods. The results demonstrated that matrine and oxymatrine had strong inhibitory activities to the conidium germination of the tested fungi. The ECso values of matrine for inhibiting the conidium germination of Marssonina brunnea, Cladosporium oxysporum, Sphaeropsis sapinea were 123μg·mL^-1, 272 μg·mL^-1, 1133 μg·mL^-1, respectively, and the EC50 values of oxymatrine for inhibiting the conidium germination of Fusarium oxysporum, Sphaeropsis sapinea were 532μg·mL^-1, 601μg·mL^-1, respectively. The hyphal growth of the fungi was also significantly inhibited by matrine and oxymatrine. The ECs0 values of matrine inhibiting the conidium germination of Sphaeropsis sapinea, Valsa pini, Fusarium oxysporum were 428μg·mL^-1, 535 μg·mL^-1, 592 μg·mL^-1, respectively. The EC50 values of oxymatrine inhibiting the conidium germination of Valsa pini, Fusarium oxysporum were 323, 618μg·mL^-1, respectively. In the synergetic tests the ECs0 values of the mixtures of thiophanate methyl (or chlorthalonil) and matrine (or oxymatrine) were lower than 34 μg·mL^-1 while their co-toxicity coefficients were significantly higher than 1130 It indicated that the mixture of the alkaloids and the chemical had potential practical utilization in controlling certain forest fungal diseases.

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期刊信息
  • 《林业研究:英文版》
  • 中国科技核心期刊
  • 主管单位:教育部
  • 主办单位:东北林业大学
  • 主编:杨传平
  • 地址:哈尔滨市动力区和兴路26号
  • 邮编:150040
  • 邮箱:jfr@mail.nefu.edu.cn
  • 电话:0451-82191144 82190464
  • 国际标准刊号:ISSN:1007-662X
  • 国内统一刊号:ISSN:23-1409/S
  • 邮发代号:
  • 获奖情况:
  • 1999年黑龙江省科技期刊审读评比农、林、水、医87...,2000年黑龙江省优秀科技期刊评比中获二等奖,省科技厅,2002年黑龙江省期刊语言文字规范检查评比获一等奖...,2002年《中国学术期刊(光盘版)检索与数据规范》...,2004年获得全国优秀农业期刊学术类二等奖,中国农学会,2008年获得第二届中国高校优秀期刊奖,教育部科技司,2008年荣获第六届中国科协期刊优秀学术论文二等奖...,2009年获教育部科技论文在线优秀期刊二等奖,
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  • 俄罗斯文摘杂志,美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰地学数据库,荷兰文摘与引文数据库,美国生物科学数据库,英国动物学记录,中国中国科技核心期刊
  • 被引量:349